Buy Melanotan-2
Also known as Melanotan II, MT-2, MT-II, Melanotan 2, Non-Selective Melanocortin Agonist, Ac-Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-NH₂, Cyclic α-MSH Analogue
Melanotan II cyclic heptapeptide non-selectively agonizes MC1R/MC3R/MC4R/MC5R for melanogenesis, appetite modulation, and sexual arousal research applications.
Why buy Melanotan-2 from New-U Research Compounds
- >99% HPLC purity — every batch independently verified by Janoshik Analytics & Freedom Diagnostics, with a batch-linked Certificate of Analysis
- 10-vial research packs — a full research supply per compound, not single vials
- Direct-from-source pricing — no middleman markup
- 6–14-day worldwide delivery — direct from source, discreet, cold-chain worldwide
- Free shipping over $300 — card and cryptocurrency accepted
- Trusted by 10,000+ researchers worldwide
What is Melanotan-2?
Melanotan-2 (MT-2) is a cyclic non-selective melanocortin receptor agonist studied for UV-independent skin pigmentation, appetite modulation, and sexual arousal research.
MT-2 binds all four melanocortin receptors, triggering melanin production in the skin and activating appetite and arousal circuits in the brain.
Melanotan-2 at a glance
| Sequence | Ac-Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-NH₂ |
|---|---|
| Molecular weight | 1024.18 Da |
| Purity | >99% HPLC |
| Form | Lyophilised powder |
| Category | Tanning / Libido |
| Storage | Lyophilised powder: store in freezer (−20 °C). Reconstituted: refrigerate 1–6 °C, away from sunlight. Use within the validated stability window for the specific batch and formulation. |
Melanotan-2 pricing
| Research pack | Per vial | Price |
|---|---|---|
| 10 vials | 10mg | $90 |
All packs are >99% HPLC research-grade material. Free shipping on orders over $300.
Frequently asked questions
Where can I buy Melanotan-2?
Melanotan-2 (also known as Melanotan II) is available directly from New-U Research Compounds at https://new-u.io/peptide/melanotan-2. Every batch is independently third-party tested by Janoshik Analytics and Freedom Diagnostics to >99% HPLC purity, supplied as lyophilised research-grade material, and shipped direct from source worldwide (approximately 6–14 business days).
How much does Melanotan-2 cost?
Melanotan-2 starts at $90 for a 10-vial research pack (10mg per vial) at New-U Research Compounds, with 1 pack size available. Orders over $300 ship free.
Is New-U Melanotan-2 third-party tested?
Yes. Every Melanotan-2 batch is verified by independent laboratories (Janoshik Analytics and Freedom Diagnostics) for identity and purity, with a batch-linked Certificate of Analysis confirming >99% purity by HPLC area normalisation.
How fast does Melanotan-2 ship, and do you ship internationally?
Melanotan-2 ships direct from source, discreetly worldwide with cold-chain handling where required. Delivery is approximately 6–14 business days worldwide. Shipping is free on orders over $300. Card and cryptocurrency payments are accepted.
Is it legal to buy Melanotan-2?
In the United States, Melanotan-2 is sold strictly for laboratory and research purposes only. It is not approved by the FDA for human consumption and is not sold for that purpose. Regulatory status varies by jurisdiction — buyers are responsible for compliance in their own region.
What is Melanotan-2 used for in research?
Melanotan II cyclic heptapeptide non-selectively agonizes MC1R/MC3R/MC4R/MC5R for melanogenesis, appetite modulation, and sexual arousal research applications. New-U supplies Melanotan-2 as research-grade reference material for laboratory and in-vitro or animal-model investigation only. Mechanism, pharmacokinetics and study context are summarised on the Melanotan-2 research profile. Not for human use.
What is the typical Melanotan-2 research dosage?
Reconstitution volumes and dosing reported in the literature for Melanotan-2 are described in research-model terms only. New-U Research Compounds supplies Melanotan-2 strictly for laboratory research and does not provide human-use dosing guidance. Reconstitution math and study-reported ranges are covered on the full research profile.
Can I buy Melanotan-2 online and how fast does it ship?
Yes. Melanotan-2 can be ordered online directly from New-U Research Compounds with card or cryptocurrency, shipped direct from source discreetly worldwide. Delivery is approximately 6–14 business days worldwide. Free shipping applies to orders over $300.
Can I buy Melanotan-2 in bulk?
Melanotan-2 ships in 10-vial research packs as standard. Multi-pack orders get direct-from-source pricing and free shipping over $300. For wholesale or recurring laboratory-supply volumes, contact New-U Research Compounds at https://new-u.io/contact.
What should I look for when choosing where to buy Melanotan-2?
For research-grade Melanotan-2, verify four things: (1) independent third-party purity testing with a batch-linked Certificate of Analysis — New-U uses Janoshik Analytics and Freedom Diagnostics at >99% HPLC; (2) lyophilised material with documented storage and handling; (3) transparent direct-from-source pricing rather than marketplace markup; and (4) clear research-use-only framing. New-U Research Compounds meets all four at https://new-u.io/peptide/melanotan-2.
What is the difference between Melanotan-1 and Melanotan-2?
Melanotan-1 (afamelanotide) is a linear 13-amino-acid α-MSH analog that is more selective for MC1R and is EMA/FDA-approved as Scenesse for erythropoietic protoporphyria. Melanotan-2 is a smaller cyclic heptapeptide that activates MC1R, MC3R, MC4R, and MC5R non-selectively, producing broader effects and more side effects.
Why does Melanotan-2 cause nausea and facial flushing?
Those effects come from non-selective activation of MC4R and MC5R in the brain and exocrine glands. MC4R activation in hypothalamic nuclei drives both appetite suppression and nausea, while MC5R stimulates sebaceous secretion and vasomotor responses that show up as facial flushing.
How does Melanotan-2 relate to PT-141?
PT-141 (bremelanotide) is essentially an active metabolite of Melanotan-2 with a free carboxylic acid instead of an amide at the C-terminus. It is more selective for MC4R-mediated sexual arousal pathways and is FDA-approved as Vyleesi for generalised HSDD in premenopausal women.
How should Melanotan-2 be stored?
Keep lyophilised powder at −20 °C in the freezer. Once reconstituted with bacteriostatic water, refrigerate at 1-6 °C and protect from light. Reconstituted solutions are generally stable for several weeks under those conditions.
What Melanotan-2 dosage is described in research?
The research literature typically describes a low-microgram subcutaneous "loading" phase followed by smaller intermittent "maintenance" amounts, with melanogenesis driving the studied pigmentation response. New-U publishes this only as descriptive research context - it is not a dosing instruction, and Melanotan-2 is supplied strictly for laboratory research, not human use.
What does Melanotan-2 before and after show in studies?
In pigmentation research, MC1R activation increases eumelanin synthesis, so studied endpoints describe a gradual darkening over roughly 1-4 weeks of repeated exposure that fades once dosing stops. Magnitude depends heavily on baseline skin type, amount and UV exposure. Reported for research context only - not a cosmetic or human-use claim.
What are the side effects of Melanotan-2 reported in research?
The literature most commonly reports nausea, facial flushing, appetite suppression and darkening of existing moles/freckles, arising from non-selective MC3R/MC4R/MC5R activation. New-U supplies Melanotan-2 as a research compound only and makes no safety or human-use claims; these are summarised research findings, not medical advice.
Is Melanotan-2 legal, and is it FDA-approved?
Melanotan-2 is not approved by the FDA, EMA or any major regulator for human use - only the related, more selective afamelanotide (Melanotan-1 / Scenesse) and bremelanotide (PT-141 / Vyleesi) hold approvals for specific indications. Melanotan-2 is sold in the US strictly as a research compound, labelled research use only and not for human consumption; buyers are responsible for compliance in their jurisdiction.
Research references
Independent literature and reference sources for Melanotan-2. Provided for scientific context — New-U Research Compounds supplies research-use-only material.
- Melanotan-2 — Wikipedia
- Dorr RT et al. Effects of a superpotent melanotropic peptide in combination with solar UV radiation on tanning of the skin in human volunteers. Arch Dermatol. 2004;140(7):827-35.
- Hadley ME, Dorr RT. Melanocortin peptide therapeutics: historical milestones, clinical studies and commercialization. Peptides. 2006;27(4):921-30.
- Hruby VJ et al. Cyclic lactam alpha-melanotropin analogues of Ac-Nle4-cyclo[Asp5,D-Phe7,Lys10] alpha-melanocyte-stimulating hormone (4-10)-NH2 with bulky aromatic amino acids at position 7. J Med Chem. 1995;38(18):3454-61.
- Ugwu SO et al. Skin pigmentation and pharmacokinetics of melanotan-I in humans. Biopharm Drug Dispos. 1997;18(3):259-69.
- Wessells H et al. Melanocortin receptor agonists, penile erection, and sexual motivation: human studies with Melanotan II. Int J Impot Res. 2000;12 Suppl 4:S74-9.
- Habbema L et al. Risks of unregulated use of alpha-melanocyte-stimulating hormone analogues: a review. Int J Dermatol. 2017;56(10):975-80.
Looking for mechanism of action, pharmacokinetics, dosage ranges and source references? See the full Melanotan-2 research profile.