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How to Store Research Compounds
Proper storage is the difference between a research compound that retains full potency and one that silently degrades into uselessness. Compounds are sensitive to temperature, light, moisture, and mechanical stress. This guide covers exactly how to store them at every stage, from arrival to the last draw.
The two states: lyophilised vs reconstituted
Compounds exist in two fundamentally different storage states, and the rules change significantly between them.
Frozen storage
Refrigerated
Storing lyophilised (unreconstituted) compounds
Lyophilised compounds are freeze-dried into a stable powder form. In this state they're relatively robust, but proper storage still matters.
Temperature
Light
UV light causes photo-oxidation of tryptophan, tyrosine, and methionine residues. Keep vials in original packaging or an opaque container. A solid-door (not glass) freezer provides inherent light protection.
Moisture
The biggest enemy of lyophilised compounds. The whole point of lyophilisation is to remove water; if it's reabsorbed, degradation reactions restart. Keep crimped caps sealed; for opened vials use parafilm and a sealed container with desiccant packets.
Long-term tips
Shipping note: Compounds shipped at ambient temperature are fine. Lyophilised compounds are stable enough to survive 3–5 days in transit without significant degradation. Once they arrive, move them to the freezer or refrigerator promptly.
Storing reconstituted compounds
Once you add bacteriostatic water to a lyophilised compound, the clock starts ticking. The compound is now dissolved in solution and subject to hydrolysis (water breaking peptide bonds), oxidation, and potential bacterial contamination.
Temperature: 2–8°C only
Refrigerate immediately after reconstitution. Never freeze a reconstituted compound unless aliquoted into single-use portions, and never refreeze a thawed aliquot.
Light protection
Reconstituted compounds are more light-sensitive than their lyophilised form because dissolved peptides are more reactive. Store in a dark area of the fridge, inside the original box, or wrap in aluminium foil.
Shelf life: 30 days
Standard guidance: use within 30 days of reconstitution at 2–8°C in BAC water. Benzyl alcohol inhibits bacterial growth, but doesn't stop chemical degradation.
Handling best practices
Do not freeze reconstituted compounds. Freezing creates ice crystals that physically damage peptide structures and cause aggregation. If you must store long-term, aliquot into single-use portions before freezing, and never refreeze a thawed aliquot.
Stability by compound class
Some compounds are more stable than others in solution.
Signs of degradation
If you notice any of the following, discard the vial.
Quick reference card
Lab-verified compounds, ready to store
All New-U Research Compounds arrive lyophilised and independently verified by Janoshik & Freedom Diagnostics. 10-vial packs, shipped worldwide.
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