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Cortagen peptide: Metabolic / Longevity research guide
In short: Cortagen (Ala-Glu-Asp-Pro / AEDP) is a synthetic tetrapeptide from the Khavinson short-peptide family, designed from the amino-acid composition of a brain-cortex peptide preparation and studied in nerve and cortical tissue models. It is studied in preclinical (cell and animal) research and is supplied strictly for laboratory use, not for human or clinical use.
Not medical advice. Cortagen is a research compound. This guide does not provide dosing, diagnosis, therapy recommendations, or claims about effects in humans.
Cortagen at a glance
What to know first
Details and limits sit in the sections below. Research use only. No unsupported scientific claims are added here.
What Cortagen is
Cortagen (Ala-Glu-Asp-Pro, "AEDP") is a four-residue synthetic peptide from the Khavinson bioregulator family, designed from a brain-cortex peptide preparation and studied in nerve and cortical tissue models.
One-paragraph overview from our research datasheet. Still scientific, but faster to read than the full mechanism list below.
Cortagen (Ala-Glu-Asp-Pro / AEDP) is a synthetic tetrapeptide from the Khavinson short-peptide family, designed from the amino-acid composition of a brain-cortex peptide preparation and studied in nerve and cortical tissue models.
Research contexts
Peer-reviewed papers discuss Cortagen in specific lab settings. The points below reflect research questions, not health claims.
Research vs. personal use: Literature describes experiments in cells and animals. That is distinct from real-world use. Our products are for laboratory research only.
Typical study contexts
Why Metabolic / Longevity research matters
Researchers study these compounds for mitochondrial function and cellular energy stress. Ageing and metabolic disease models are common.
Mechanisms (technical review)
Our datasheet lists mechanistic themes from preclinical work. These are research endpoints, not health claims.
Lab handling & preparation
Common Questions People Are Asking
What is Cortagen?
Cortagen is the name used for the synthetic tetrapeptide Ala-Glu-Asp-Pro (AEDP), designed by the Khavinson group from the amino-acid composition of a brain-cortex peptide preparation. It is supplied here as a laboratory research powder only.
How does Cortagen differ from Epitalon?
They share the Ala-Glu-Asp stem. Epitalon ends in glycine (Ala-Glu-Asp-Gly) and Cortagen in proline (Ala-Glu-Asp-Pro). A study from the originating group notes that the two behaved differently in the same experiment, with Epitalon affecting immune and haemostasis markers in hypophysectomised birds where Cortagen did not.
What does the research on Cortagen show?
In rats, a 10-day course was reported to speed regenerating nerve fibres and raise conduction velocity after sciatic-nerve transection. In mice it changed expression of 234 of 15,247 cDNA clones in the heart. Several comparisons with related peptides were weaker or null. All of it is preclinical.
Is there a Certificate of Analysis for Cortagen?
Not yet. No independent analytical report has been published for this material, so no purity figure is quoted.
Is there human data on Cortagen?
No controlled human trial was found. Cortagen is sold strictly for in-vitro and preclinical research, not for human or veterinary use.
Is this page medical advice? Can I use Cortagen for my health?
No, and no. This article is educational only. We do not provide dosing, medical recommendations, or health claims. Our products are sold strictly for laboratory research, not for personal use of any kind.
Where do I find Cortagen specs, purity certificates and pricing?
Open the shop listing via “View product details.” There you will see concentration, purity grade, and available SKUs with current pricing. No current Certificate of Analysis is published for Cortagen yet; published certificates are listed at /coa.
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Continue Cortagen research
Analytical evidence, comparisons and current research for this compound. Research use only.
Scientific sources & further reading
Primary literature and registries for Cortagen, plus mainstream coverage of the peptide category. Research use only - not medical advice.
Databases & literature:
Peptides in the news:
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Also known as: Cortagen, Cortagene, AEDP, Ala-Glu-Asp-Pro, H-Ala-Glu-Asp-Pro-OH, alanyl-glutamyl-aspartyl-proline, Khavinson cortex and nerve bioregulator
PRECISION. PURITY. PERFORMANCE.
Research peptides. Third-party Certificates of Analysis (Janoshik Analytical & Freedom Diagnostics) are published on the website. Supplied strictly for laboratory research use.
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Research use only - all claims made on this site are for testing and research use only. Purchasers must be 21 years of age or older.
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