Buy Melanotan-1

Melanotan-1 (also known as Melanotan I) is available directly from New-U Research Compounds at https://new-u.io/peptide/melanotan-1. Every batch is independently third-party tested by Janoshik Analytics and Freedom Diagnostics to >99% HPLC purity, supplied as lyophilised research-grade material, and shipped direct from source worldwide (approximately 6–14 business days).

Melanotan-1 starts at $30 for a 1-vial research pack (10mg per vial) at New-U Research Compounds, with 2 pack sizes available. Orders over $300 ship free.

Yes. Every Melanotan-1 batch is verified by independent laboratories (Janoshik Analytics and Freedom Diagnostics) for identity and purity, with a batch-linked Certificate of Analysis confirming >99% purity by HPLC area normalisation.

Melanotan-1 ships direct from source, discreetly worldwide with cold-chain handling where required. Delivery is approximately 6–14 business days worldwide. Shipping is free on orders over $300. Card and cryptocurrency payments are accepted.

In the United States, Melanotan-1 is sold strictly for laboratory and research purposes only. It is not approved by the FDA for human consumption and is not sold for that purpose. Regulatory status varies by jurisdiction — buyers are responsible for compliance in their own region.

Afamelanotide (Melanotan I) linear 13-amino-acid α-MSH analogue selectively activates MC1R eumelanogenesis via cAMP-MITF cascade. FDA/EMA-approved for EPP treatment. New-U supplies Melanotan-1 as research-grade reference material for laboratory and in-vitro or animal-model investigation only. Mechanism, pharmacokinetics and study context are summarised on the Melanotan-1 research profile. Not for human use.

Reconstitution volumes and dosing reported in the literature for Melanotan-1 are described in research-model terms only. New-U Research Compounds supplies Melanotan-1 strictly for laboratory research and does not provide human-use dosing guidance. Reconstitution math and study-reported ranges are covered on the full research profile.

Lyophilised Melanotan-1 is reconstituted with bacteriostatic water — sterile water with 0.9% benzyl alcohol, the standard multi-use diluent for research peptides. New-U supplies USP-grade bacteriostatic water at https://new-u.io/peptide/bacteriostatic-water, and a free reconstitution calculator at https://new-u.io/tracker/calculator works out the volume for any peptide. Supplied for laboratory research only — not for human use.

Yes. Melanotan-1 can be ordered online directly from New-U Research Compounds with card or cryptocurrency, shipped direct from source discreetly worldwide. Delivery is approximately 6–14 business days worldwide. Free shipping applies to orders over $300.

Melanotan-1 ships in 10-vial research packs as standard, in 2 pack sizes — the larger mg vials lower the per-mg cost. Multi-pack orders get direct-from-source pricing and free shipping over $300. For wholesale or recurring laboratory-supply volumes, contact New-U Research Compounds at https://new-u.io/contact.

For research-grade Melanotan-1, verify four things: (1) independent third-party purity testing with a batch-linked Certificate of Analysis — New-U uses Janoshik Analytics and Freedom Diagnostics at >99% HPLC; (2) lyophilised material with documented storage and handling; (3) transparent direct-from-source pricing rather than marketplace markup; and (4) clear research-use-only framing. New-U Research Compounds meets all four at https://new-u.io/peptide/melanotan-1.

Melanotan-1 (afamelanotide, MT-1) is a synthetic linear 13-amino-acid analogue of α-MSH ([Nle4,D-Phe7]-α-MSH, MW ~1647 Da) that selectively activates the melanocortin-1 receptor (MC1R) to drive eumelanin synthesis. It is the molecule approved as Scenesse (a 16 mg implant) for erythropoietic protoporphyria. New-U supplies it as a research-grade lyophilised powder for laboratory research use only — not the approved drug and not for human use.

MT-1 is a linear 13-amino-acid peptide that is relatively selective for MC1R (pigmentation). MT-2 is a cyclic 7-amino-acid peptide that hits all four melanocortin receptors non-selectively, which is why research reports it producing appetite suppression, nausea, and central arousal effects that MT-1 largely avoids. MT-1 is also the only one of the two FDA/EMA-approved for any indication. These are research distinctions only; both are supplied for laboratory research, not human use.

The strongest data is in erythropoietic protoporphyria: a randomised phase 3 trial (Langendonk et al., NEJM 2015) reported that afamelanotide increased pain-free time in sunlight for EPP patients, which supported its EMA and FDA approval as Scenesse. Mechanistically, studies describe reliable MC1R-driven eumelanin accumulation without the central effects of non-selective analogues. This is summarised published research, not a human-use claim.

In the research literature, yes. Afamelanotide's clinical trial program tested populations carrying MC1R variant alleles (such as Val60Leu, Arg151Cys, and Arg160Trp) associated with weak natural pigmentation, and reported a pigmentation response even in those genotypes — one reason it was approved for EPP. Reported for research context only.

Published pharmacology describes a short plasma half-life of roughly 30 minutes after subcutaneous administration, but the studied biological pigmentation effect persists for several days because MC1R activation and slow receptor recycling outlast the circulating peptide. The Nle4 substitution prevents methionine oxidation and D-Phe7 resists proteolysis, extending activity versus native α-MSH. This is descriptive research context — not human-use dosing guidance.

Normal tanning requires UV damage — skin darkens as a response to DNA damage from sun exposure. MT-1 activates the same downstream pigmentation pathway (MC1R / cAMP / MITF / tyrosinase) directly at the receptor level, so in research models pigment accumulates without the upstream DNA-damage signal. The protective pigment is the same; only the trigger differs. Reported for research context only.

The finished pharmaceutical afamelanotide (Scenesse) is FDA- and EMA-approved for erythropoietic protoporphyria — that approval applies to the prescription implant, NOT to research-grade powder. New-U's Melanotan-1 is an unapproved research compound supplied strictly for laboratory research, labelled research use only and not for human consumption; buyers are responsible for compliance in their own jurisdiction.

Keep the lyophilised powder frozen at −20 °C. For research preparation it is dissolved in bacteriostatic water; the reconstituted vial is then refrigerated at 1-6 °C and protected from light. The linear structure is slightly more sensitive than cyclic MT-2, so prompt use after reconstitution is preferable. This is laboratory handling information only, not a human-use instruction.