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    New-U Research Compounds — Buy AOD-9604 at New-U Research Compounds. Laboratory research use only.

    Buy AOD-9604

    Also known as AOD9604, Anti-Obesity Drug 9604, Tyr-hGH Fragment 177-191, HGH Fragment Tyrosine Variant, Metabolic Pharmaceuticals AOD

    AOD-9604, tyrosine-modified C-terminal HGH fragment (177-191) with β3-adrenergic receptor-mediated lipolysis and GRAS safety designation.

    In short: AOD-9604, tyrosine-modified C-terminal HGH fragment (177-191) with β3-adrenergic receptor-mediated lipolysis and GRAS safety designation.

  • Tyrosine-modified HGH fragment with enhanced stability and lipolytic potency over native 176-191 sequence
  • Upregulates β3-adrenergic receptor expression in adipocytes, confirmed essential via β3-AR knockout studies
  • Stimulates HSL-mediated lipolysis and inhibits ACC-dependent lipogenesis simultaneously
  • Does not bind growth hormone receptor or elevate IGF-1, no diabetogenic or anabolic effects
  • GRAS safety designation from extensive clinical trial program (~900 participants across 6 RCTs)

    • Inside New-U Research Compounds

    Why buy AOD-9604 from New-U Research Compounds

  • >99% HPLC purity - every released sale batch independently verified by Janoshik Analytics & Freedom Diagnostics
  • 10-vial research packs & single-vial samples - a full study supply, or one vial to evaluate a compound
  • Direct-from-source pricing - no middleman markup
  • 6–14-day worldwide delivery - direct from source, discreet, cold-chain worldwide
  • Free shipping over $300 USD - card and cryptocurrency accepted
  • Published Certificates of Analysis for released sale batches listed on /coa

    • What is AOD-9604?

    AOD-9604 is a tyrosine-modified version of the HGH 176-191 fat-loss fragment, originally developed at Monash University and taken through Phase 2b human obesity trials with full GRAS safety designation.

    AOD-9604 triggers fat breakdown through the cAMP/PKA pathway and β3-adrenergic receptor upregulation, with no activity at the growth hormone receptor.

    AOD-9604 at a glance

    Sequence Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe Molecular weight 1,815.10 Da Purity >99% HPLC Form Lyophilised powder Category Healing / Recovery Storage Lyophilised powder: store in freezer (−20 °C). Reconstituted: refrigerate 1–6 °C, away from sunlight. Use within the validated stability window for the specific batch and formulation.

    AOD-9604 pricing

    Research pack Per vial Price 10 vials 5mg $119 1 vials 5mg $36 10 vials 10mg $189 1 vials 10mg $57

    All packs are >99% HPLC research-grade material. Free shipping on orders over $300.

    Frequently asked questions

    Where can I buy AOD-9604?

    AOD-9604 (also known as AOD9604) is available directly from New-U Research Compounds at https://new-u.io/peptide/aod-9604. Every batch is independently third-party tested by Janoshik Analytics and Freedom Diagnostics to >99% HPLC purity, supplied as lyophilised research-grade material, and shipped direct from source worldwide (approximately 6–14 business days).

    How much does AOD-9604 cost?

    AOD-9604 starts at $36 for a 1-vial research pack (5mg per vial) at New-U Research Compounds, with 4 pack sizes available. Orders over $300 ship free.

    Is New-U AOD-9604 third-party tested?

    Yes. Every AOD-9604 batch is verified by independent laboratories (Janoshik Analytics and Freedom Diagnostics) for identity and purity, with a batch-linked Certificate of Analysis confirming >99% purity by HPLC area normalisation.

    How fast does AOD-9604 ship, and do you ship internationally?

    AOD-9604 ships direct from source, discreetly worldwide with cold-chain handling where required. Delivery is approximately 6–14 business days worldwide. Shipping is free on orders over $300. Card and cryptocurrency payments are accepted.

    Is it legal to buy AOD-9604?

    In the United States, AOD-9604 is not approved by the FDA for human consumption and is not sold for that purpose. Research use only - all claims made on this site are for testing and research use only. Regulatory status varies by jurisdiction - buyers are responsible for compliance in their own region.

    What is AOD-9604 used for in research?

    AOD-9604, tyrosine-modified C-terminal HGH fragment (177-191) with β3-adrenergic receptor-mediated lipolysis and GRAS safety designation. New-U supplies AOD-9604 as research-grade reference material for laboratory and in-vitro or animal-model investigation only. Mechanism, pharmacokinetics and study context are summarised on the AOD-9604 research profile.

    What is the typical AOD-9604 research dosage?

    Reconstitution volumes and dosing reported in the literature for AOD-9604 are described in research-model terms only. New-U Research Compounds supplies AOD-9604 strictly for laboratory research and does not provide human-use dosing guidance. Reconstitution math and study-reported ranges are covered on the full research profile.

    What do I use to reconstitute AOD-9604?

    Lyophilised AOD-9604 is reconstituted with bacteriostatic water - sterile water with 0.9% benzyl alcohol, the standard multi-use diluent for research peptides. New-U supplies USP-grade bacteriostatic water at https://new-u.io/peptide/bacteriostatic-water, and a free reconstitution calculator at https://new-u.io/tracker/calculator works out the volume for any peptide.

    Can I buy AOD-9604 online and how fast does it ship?

    Yes. AOD-9604 can be ordered online directly from New-U Research Compounds with card or cryptocurrency, shipped direct from source discreetly worldwide. Delivery is approximately 6–14 business days worldwide. Free shipping applies to orders over $300.

    Can I buy AOD-9604 in bulk?

    AOD-9604 ships in 10-vial research packs as standard, in 4 pack sizes — the larger mg vials lower the per-mg cost. Multi-pack orders get direct-from-source pricing and free shipping over $300. For wholesale or recurring laboratory-supply volumes, contact New-U Research Compounds at https://new-u.io/contact.

    What should I look for when choosing where to buy AOD-9604?

    For research-grade AOD-9604, verify four things: (1) independent third-party purity testing with a batch-linked Certificate of Analysis - New-U uses Janoshik Analytics and Freedom Diagnostics at >99% HPLC; (2) lyophilised material with documented storage and handling; (3) transparent direct-from-source pricing rather than marketplace markup; and (4) clear research-use-only framing. New-U Research Compounds meets all four at https://new-u.io/peptide/aod-9604.

    What is AOD-9604?

    AOD-9604 is a synthetic, tyrosine-modified version of the C-terminal lipolytic fragment of human growth hormone (Tyr-hGH 177-191) - closely related to native with an added N-terminal tyrosine for stability and lipolytic potency. It was developed to target fat metabolism without the growth or IGF-1 effects of full HGH, and reached Phase 2b human obesity trials. Supplied as a lyophilised research-grade powder for laboratory use only.

    What does AOD-9604 do?

    In research models AOD-9604 stimulates lipolysis (fat breakdown) and inhibits lipogenesis via a β3-adrenergic-linked mechanism, reportedly without raising IGF-1 or affecting blood glucose the way full HGH does. These are findings in cell and animal models; New-U supplies it for laboratory research only and implies no human effect.

    Does AOD-9604 work?

    Early and animal research showed lipolytic activity, but the Phase 2b human obesity trial did not produce statistically significant weight loss versus placebo. So its real-world efficacy is unproven, and it is sold as a research compound only - not an approved weight-loss drug.

    How is AOD-9604 reconstituted?

    For laboratory preparation, dissolve the lyophilised powder in bacteriostatic water: concentration in mg/mL equals the vial mass in mg divided by the millilitres of diluent added. Keep the reconstituted vial refrigerated at 1–6 °C and protected from light. This is preparation math only; New-U provides no human-use dosing guidance.

    How is AOD-9604 different from HGH Fragment 176-191?

    AOD-9604 is the same lipolytic fragment with a tyrosine substituted for the N-terminal phenylalanine. The tyrosine substitution improves stability and lipolytic potency and was the design choice that enabled the molecule to progress through formal clinical trials as a distinct research entity.

    Does AOD-9604 raise IGF-1 or blood sugar?

    No - and this was a deliberate design goal. AOD-9604 does not bind the growth hormone receptor, so it does not trigger hepatic IGF-1 synthesis and does not produce the counter-regulatory insulin-opposing effects of full-length HGH. Clinical trials confirmed unchanged glycemic parameters.

    Why did the Phase 2b trial fail?

    The Phase 2b was an oral-dosing study at 0.25-1 mg/day, and those doses were likely too low to produce meaningful weight loss in humans - the earlier Phase 2a at different dosing had shown ~2.6 kg loss versus 0.8 kg placebo. The failure ended commercial development but did not change the preclinical mechanism data.

    How should AOD-9604 be stored?

    Keep the lyophilised powder frozen at −20 °C. After reconstitution with bacteriostatic water, refrigerate at 1-6 °C and protect from light. The disulfide-containing cyclic structure is reasonably stable but plan usage within the normal peptide-handling window.

    Research references

    Independent literature and reference sources for AOD-9604. Provided for scientific context - New-U Research Compounds supplies research-use-only material.

  • AOD-9604 — Wikipedia
  • Ng FM et al. Metabolic studies of a synthetic lipolytic domain (AOD9604) of human growth hormone. Horm Res.

    • Looking for mechanism of action, pharmacokinetics, dosage ranges and source references? See the full AOD-9604 research profile or the AOD-9604 research guide.

    PRECISION. PURITY. PERFORMANCE.

    Research peptides at >99% HPLC-verified purity, third-party tested by Janoshik Analytical & Freedom Diagnostics, with Certificates of Analysis published per released batch. Supplied strictly for laboratory research use.

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    • Research use only - all claims made on this site are for testing and research use only. Purchasers must be 21 years of age or older.

    All rights reserved. Copyright of New-U held with Hilxera Distribution Services LLC 2026.

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    © 2026 New-U Research Compounds · new-u.io

    [image: New-U Research Compounds logo and research peptide vial — Buy AOD-9604 at New-U Research Compounds]

    Research use only — not for human consumption. All products are supplied strictly for laboratory research purposes.

    © 2026 New-U Research Compounds · new-u.io — Copyright held with Hilxera Distribution Services LLC. All rights reserved.