Buy Thymosin Alpha-1
Also known as Thymalfasin, Tα1, Ta1, Zadaxin, Thymosin α1, Thymosin Alpha 1, SciClone Thymalfasin, Immune Modulator Peptide
Thymosin Alpha-1 (Zadaxin) 28-amino-acid thymic peptide activates TLR2/3/4/7/9 signaling for T-cell maturation. Approved in 30+ countries for immunomodulation.
Why buy Thymosin Alpha-1 from New-U Research Compounds
- >99% HPLC purity — every batch independently verified by Janoshik Analytics & Freedom Diagnostics, with a batch-linked Certificate of Analysis
- 10-vial research packs & single-vial samples — a full study supply, or one vial to trial a compound
- Direct-from-source pricing — no middleman markup
- 6–14-day worldwide delivery — direct from source, discreet, cold-chain worldwide
- Free shipping over $300 — card and cryptocurrency accepted
- Trusted by 10,000+ researchers worldwide
What is Thymosin Alpha-1?
Thymosin Alpha-1 (Zadaxin) is a 28-amino-acid thymic peptide that activates multiple Toll-like receptors to rebalance both innate and adaptive immunity, approved as an immunomodulator in more than 30 countries.
Thymosin Alpha-1 activates innate immune Toll-like receptors while supporting T-cell maturation, reshaping both arms of the immune system rather than just boosting or suppressing it.
Thymosin Alpha-1 at a glance
| Sequence | Ac-SDAAVDTSSEITTKDLKEKKEVVEEAEN |
|---|---|
| Molecular weight | 3108 Da |
| Purity | >99% HPLC |
| Form | Lyophilised powder |
| Category | Healing / Recovery |
| Storage | Lyophilised powder: store in freezer (−20 °C). Reconstituted: refrigerate 1–6 °C, away from sunlight. Use within the validated stability window for the specific batch and formulation. |
Thymosin Alpha-1 pricing
| Research pack | Per vial | Price |
|---|---|---|
| 10 vials | 10mg | $160 |
| 1 vials | 10mg | $48 |
All packs are >99% HPLC research-grade material. Free shipping on orders over $300.
Frequently asked questions
Where can I buy Thymosin Alpha-1?
Thymosin Alpha-1 (also known as Thymalfasin) is available directly from New-U Research Compounds at https://new-u.io/peptide/thymosin-alpha-1. Every batch is independently third-party tested by Janoshik Analytics and Freedom Diagnostics to >99% HPLC purity, supplied as lyophilised research-grade material, and shipped direct from source worldwide (approximately 6–14 business days).
How much does Thymosin Alpha-1 cost?
Thymosin Alpha-1 starts at $48 for a 1-vial research pack (10mg per vial) at New-U Research Compounds, with 2 pack sizes available. Orders over $300 ship free.
Is New-U Thymosin Alpha-1 third-party tested?
Yes. Every Thymosin Alpha-1 batch is verified by independent laboratories (Janoshik Analytics and Freedom Diagnostics) for identity and purity, with a batch-linked Certificate of Analysis confirming >99% purity by HPLC area normalisation.
How fast does Thymosin Alpha-1 ship, and do you ship internationally?
Thymosin Alpha-1 ships direct from source, discreetly worldwide with cold-chain handling where required. Delivery is approximately 6–14 business days worldwide. Shipping is free on orders over $300. Card and cryptocurrency payments are accepted.
Is it legal to buy Thymosin Alpha-1?
In the United States, Thymosin Alpha-1 is sold strictly for laboratory and research purposes only. It is not approved by the FDA for human consumption and is not sold for that purpose. Regulatory status varies by jurisdiction — buyers are responsible for compliance in their own region.
What is Thymosin Alpha-1 used for in research?
Thymosin Alpha-1 (Zadaxin) 28-amino-acid thymic peptide activates TLR2/3/4/7/9 signaling for T-cell maturation. Approved in 30+ countries for immunomodulation. New-U supplies Thymosin Alpha-1 as research-grade reference material for laboratory and in-vitro or animal-model investigation only. Mechanism, pharmacokinetics and study context are summarised on the Thymosin Alpha-1 research profile. Not for human use.
What is the typical Thymosin Alpha-1 research dosage?
Reconstitution volumes and dosing reported in the literature for Thymosin Alpha-1 are described in research-model terms only. New-U Research Compounds supplies Thymosin Alpha-1 strictly for laboratory research and does not provide human-use dosing guidance. Reconstitution math and study-reported ranges are covered on the full research profile.
What do I use to reconstitute Thymosin Alpha-1?
Lyophilised Thymosin Alpha-1 is reconstituted with bacteriostatic water — sterile water with 0.9% benzyl alcohol, the standard multi-use diluent for research peptides. New-U supplies USP-grade bacteriostatic water at https://new-u.io/peptide/bacteriostatic-water, and a free reconstitution calculator at https://new-u.io/tracker/calculator works out the volume for any peptide. Supplied for laboratory research only — not for human use.
Can I buy Thymosin Alpha-1 online and how fast does it ship?
Yes. Thymosin Alpha-1 can be ordered online directly from New-U Research Compounds with card or cryptocurrency, shipped direct from source discreetly worldwide. Delivery is approximately 6–14 business days worldwide. Free shipping applies to orders over $300.
Can I buy Thymosin Alpha-1 in bulk?
Thymosin Alpha-1 ships in 10-vial research packs as standard, in 2 pack sizes — the larger mg vials lower the per-mg cost. Multi-pack orders get direct-from-source pricing and free shipping over $300. For wholesale or recurring laboratory-supply volumes, contact New-U Research Compounds at https://new-u.io/contact.
What should I look for when choosing where to buy Thymosin Alpha-1?
For research-grade Thymosin Alpha-1, verify four things: (1) independent third-party purity testing with a batch-linked Certificate of Analysis — New-U uses Janoshik Analytics and Freedom Diagnostics at >99% HPLC; (2) lyophilised material with documented storage and handling; (3) transparent direct-from-source pricing rather than marketplace markup; and (4) clear research-use-only framing. New-U Research Compounds meets all four at https://new-u.io/peptide/thymosin-alpha-1.
What is Thymosin Alpha-1 and how does it work?
Thymosin Alpha-1 is a 28-amino-acid N-terminally acetylated thymic peptide derived from prothymosin alpha. It works by directly engaging multiple Toll-like receptors (TLR2/3/4/7/9) on innate immune cells, triggering IRF3, NF-κB, p38MAPK and MyD88 signalling, while also supporting maturation of CD4+/CD8+ T-cells, NK-cell cytotoxicity, and dendritic-cell antigen presentation. This dual innate-plus-adaptive action is why it is described as an immune rebalancer rather than a simple stimulant.
What does "immunomodulator" mean versus "immunostimulant"?
An immunostimulant broadly revs up immune activity; an immunosuppressant broadly shuts it down. An immunomodulator like Tα1 rebalances — it can amplify weak responses in immune-exhausted states like chronic viral infection, while helping calm overactivation in conditions like sepsis. The same molecule can do both because the immune system regulates itself differently in different states.
What does the clinical research actually show?
The evidence is genuinely mixed. Chronic hepatitis B studies reported higher HBV DNA clearance versus controls, and COVID-19 work suggested restoration of lymphocyte counts and reversal of T-cell exhaustion. But the rigorous multicentre phase-3 TESTS sepsis trial (2025) found no significant 28-day mortality benefit. So while the mechanism is well characterised, the clinical efficacy picture is not uniformly positive — and none of this is human-use guidance.
What dosing appears in the published literature?
Published clinical trials describe a 1.6 mg dose (approximately 900 μg/m² of body surface area) administered subcutaneously twice weekly, the schedule used across most of the sepsis, hepatitis B, and immune-support studies. Subcutaneous Tmax is roughly 2 hours and serum half-life around 2 hours, with return toward baseline within 24 hours. These are descriptive research parameters only; Tα1 is supplied for laboratory research.
How does Thymosin Alpha-1 differ from Thymulin or Thymopoietin?
They are all thymic peptides but completely different molecules with different mechanisms. Tα1 is a 28-residue peptide derived from prothymosin alpha that binds TLRs and supports T-cell maturation. Thymulin is a nonapeptide that requires zinc for activity, and thymopoietin is a 49-residue polypeptide. They are sometimes grouped together as "thymic factors" but act distinctly.
Is Thymosin Alpha-1 approved or legal?
Thymosin Alpha-1 is marketed as Zadaxin and approved as an immunomodulator in more than 30 countries, and it holds FDA orphan-drug designation for several indications — but it is not an FDA-approved drug for general therapeutic use in the United States. New-U supplies it strictly as a research-grade compound for in-vitro and preclinical laboratory research, not for human use; buyers are responsible for local compliance.
How should Thymosin Alpha-1 be stored and reconstituted?
Keep the lyophilised powder frozen at −20 °C. After reconstitution with bacteriostatic water, refrigerate at 1–6 °C and protect from light. Tα1 is reasonably stable in solution within the normal peptide-handling window; avoid repeated freeze-thaw cycles. This is laboratory handling guidance only.
Research references
Independent literature and reference sources for Thymosin Alpha-1. Provided for scientific context — New-U Research Compounds supplies research-use-only material.
Looking for mechanism of action, pharmacokinetics, dosage ranges and source references? See the full Thymosin Alpha-1 research profile or the Thymosin Alpha-1 research guide.